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Side effects

Nausea, reflux, constipation and more — how people cope, and when to call a doctor.

Discussions

24 Oct 20262 answersSeeded example

What were your first four weeks on semaglutide actually like?

People starting semaglutide commonly report reduced appetite within days, mild nausea in weeks 1–2 that often settles, and quieter food noise — with wide individual variation.

Treatment expectationsAppetite & satietySide effects
18 Oct 20262 answersSeeded example

How do you manage nausea on a GLP-1 without giving up?

Members report that smaller meals, eating slowly, avoiding fried food near dose day, and staying hydrated helped most with GLP-1 nausea — and that persistent or severe nausea is a reason to call your doctor, not push through.

Side effectsNutrition & meals

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